منابع مشابه
Metabolomics and Cell Therapy in Diabetes Mellitus
Diabetes with a broad spectrum of complications has become a global epidemic metabolic disorder. Till now, several pharmaceutical and non-pharmaceutical therapeutic approaches were applied for its treatment. Cell-based therapies have become promising methods for diabetes treatment. Better understanding of diabetes pathogenesis and identification of its specific biomarkers along with evaluation ...
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Gestational diabetes mellitus (GDM) is defined as glucose intolerance first diagnosed during the second or third trimester of pregnancy. The treatment aims at glycemic control through changes in the patient's diet with or without exercise, but some patients need insulin therapy. An alternative would be to use oral hypoglycemic agents such as glibenclamide (GLIB). The present study aims to analy...
متن کاملPharmacogenomics of glibenclamide in patients with type 2 diabetes mellitus: A systematic review
Introduction: One of the most widely used anti-diabetic drugs is sulfonylureas, which is often used as one of the first-line drugs in the treatment of type 2 diabetes. Due to the effect of the patient's genetic structure on the drug response (personalized medicine), the identification of genetic variations not only reduces the rate of adverse drug reactions but can also predict the effectivenes...
متن کاملDiabetes Mellitus in the Elderly
Nach einer Einleitung und Diskussion tiber die Eingenschaften der diabetischen Krankheiten wurde ausflihrlich trber die Aetiologie und Pathophysiologie der Zuckerankheiten,insbesondere der Altersdiabetis,gesprochen.Nach der symptomalogie der Diabetis haben wir die ncueste Einteilung der Zuckerkrankheiten genannt und die Untcrsuchungsmethoden,die heute Uhlich sind,erwahnt;dazu wurden unsere M...
متن کاملGene therapy for diabetes mellitus.
1. This review describes experimental approaches to test the feasibility of using gene therapy to administer insulin to type 1 and type 2 diabetic patients. Two approaches, i.e. ex vivo and in vivo transfer of the insulin gene, are described. 2. Substantial progress has been made in recent years in engineering glucose-responsive beta-cell lines that have been genetically engineered to prolifera...
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ژورنال
عنوان ژورنال: BMJ
سال: 1970
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5709.570